Cytotoxic activity of glycoalkaloids extract from fruits of Solanum lycocarpum A. St.-Hil
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چکیده
منابع مشابه
Cytotoxic activity of glycoalkaloids extract from fruits of Solanum lycocarpum A. St.-Hil
Background Phytochemical analysis of the fruits of Solanum lycocarpum, popularly known as “fruit of the wolf”, showed high concentrations of steroidal alkaloids, such as solasonine and solamargine which are substances with potential cytotoxic activity [1]. The cytotoxic activity displayed by these compounds may be due to presence of sugar moieties (rhamnose). Since there is interaction of glyco...
متن کاملEvaluation of antifungal activity of glycoalkaloids from the Solanum lycocarpum St. Hil (lobeira) in the cell membrane of dermatophyte of Trichophyton rubrum
Background The dermatophytes belong to one of the main groups of pathogenic fungus, characterized by the use of the host’s keratin for its nutrition, which are the most common cause of fungal infection in the world, affecting millions of individuals annually, causing a huge economic impact [1]. Therefore, there was an increase in the search for new antifungal agents from natural sources, becaus...
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Ethanol extract and fractions obtained from leaves of Solanum lycocarpum were examined in order to determine their phenolic composition, antioxidant, antibacterial, anti-inflammatory, and cytotoxic potential. High performance liquid chromatography coupled with DAD analysis indicated that the flavonoids apigenin and kaempferol were the main phenolic compounds present in dichloromethane and ethyl...
متن کاملInbreeding effects in Solanum lycocarpum A. St.-Hil populations, an endangered species of the Brazilian Cerrado.
The inbreeding effective population size is an estimate of inbreeding and genetic drift in populations. It is an important tool for conservation genetics because it represents the number of individuals that are effectively contributing alleles to the subsequent generations. Several studies have been published in the last decades on the genetic structure of natural plant populations of the Cerra...
متن کاملCytotoxic and genotoxic effects of Solanum lycocarpum St.-Hil (Solanaceae) on the cell cycle of Lactuca sativa and Allium cepa
Solanum lycocarpum St.-Hil popularly known as ‘fruta-de-lobo’ or ‘lobeira’ is native to the Brazilian Cerrado, and used in folk medicine due to its phytotherapic properties. The action of S. lycocarpum on the cell cycle and chromosomes in order to demonstrate whether there are aneugenic and/or clastogenic effects is unknown. Thus, this study aimed at investigating the cytotoxic and genotoxic po...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2014
ISSN: 1753-6561
DOI: 10.1186/1753-6561-8-s4-p7